Inducible expression of human hepatitis B virus (HBV) in stably transfected hepatoblastoma cells: a novel system for screening potential inhibitors of HBV replication.

We report the development and isolation of a cell line, termed HepAD38, that replicates human hepatitis B virus (HBV) under conditions that can be regulated with tetracycline. In the presence of the antibiotic, this cell line is free of virus due to the repression of pregenomic (pg) RNA synthesis. U...

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Bibliografski detalji

Izdano u:	Antimicrob Agents Chemother
Glavni autori:	Ladner, S K, Otto, M J, Barker, C S, Zaifert, K, Wang, G H, Guo, J T, Seeger, C, King, R W
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 1997
Teme:	Research Article
Online pristup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163991/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9257747/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.8.1715
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