Stereoselective interaction of the azole antifungal agent SCH39304 with the cytochrome P-450 monooxygenase system isolated from Cryptococcus neoformans.

We investigated the stereoselective inhibition of growth and ergosterol biosynthesis by SCH39304 in the pathogenic fungus Cryptococcus neoformans obtained from four AIDS patients who failed fluconazole therapy and compared the results to those obtained with a wild-type strain. For all strains, the M...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Lamb, D C, Baldwin, B C, Kwon-Chung, K J, Kelly, S L
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163941/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9210667/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.7.1465
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