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Stereoselective interaction of the azole antifungal agent SCH39304 with the cytochrome P-450 monooxygenase system isolated from Cryptococcus neoformans.

We investigated the stereoselective inhibition of growth and ergosterol biosynthesis by SCH39304 in the pathogenic fungus Cryptococcus neoformans obtained from four AIDS patients who failed fluconazole therapy and compared the results to those obtained with a wild-type strain. For all strains, the M...

詳細記述

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書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Lamb, D C, Baldwin, B C, Kwon-Chung, K J, Kelly, S L
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 1997
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163941/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9210667/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.7.1465
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