Attenuation of gentamicin-induced nephrotoxicity in rats by fleroxacin.

The effect of fleroxacin on gentamicin-induced nephrotoxicity was evaluated with female Sprague-Dawley rats. Animals were injected during 4 or 10 days with saline (NaCl; 0.9%), gentamicin alone at doses of 10 and 40 mg/kg of body weight/12 h (subcutaneously), fleroxacin alone at a dose of 25 mg/kg/1...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Beauchamp, D, Laurent, G, Grenier, L, Gourde, P, Zanen, J, Heuson-Stiennon, J A, Bergeron, M G
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1997
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163893/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9174177/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.6.1237
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