1592U89, a novel carbocyclic nucleoside analog with potent, selective anti-human immunodeficiency virus activity.

1592U89, (-)-(1S,4R)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclo pentene-1-methanol, is a carbocyclic nucleoside with a unique biological profile giving potent, selective anti-human immunodeficiency virus (HIV) activity. 1592U89 was selected after evaluation of a wide variety of analogs c...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Daluge, S M, Good, S S, Faletto, M B, Miller, W H, St Clair, M H, Boone, L R, Tisdale, M, Parry, N R, Reardon, J E, Dornsife, R E, Averett, D R, Krenitsky, T A
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1997
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163855/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9145874/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.5.1082
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