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A mutation in the D,D-carboxypeptidase penicillin-binding protein 3 of Streptococcus pneumoniae contributes to cefotaxime resistance of the laboratory mutant C604.

Cefotaxime resistance in laboratory mutant C604 of Streptococcus pneumoniae, for which the MIC is 1.5 microg/ml, is independent of alterations in high-molecular-mass penicillin-binding protein (PBP) 1a. Instead, a point mutation in PBP 3, the D,D-carboxypeptidase of this organism, caused a reduced a...

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Publicado en:Antimicrob Agents Chemother
Principais autores: Krauss, J, Hakenbeck, R
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1997
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163829/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9145848/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.5.936
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