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A mutation in the D,D-carboxypeptidase penicillin-binding protein 3 of Streptococcus pneumoniae contributes to cefotaxime resistance of the laboratory mutant C604.

Cefotaxime resistance in laboratory mutant C604 of Streptococcus pneumoniae, for which the MIC is 1.5 microg/ml, is independent of alterations in high-molecular-mass penicillin-binding protein (PBP) 1a. Instead, a point mutation in PBP 3, the D,D-carboxypeptidase of this organism, caused a reduced a...

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Bibliografische gegevens
Hoofdauteurs: Krauss, J, Hakenbeck, R
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1997
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC163829/
https://ncbi.nlm.nih.gov/pubmed/9145848
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