Suspicion of quinolone active metabolite following discrepancy between predicted and experimental urine bactericidal activities.
The prediction of urine antibacterial activity from pharmacological and microbiological parameters was assessed by using experimental urine levels and urine bactericidal titers determined up to 72 h after a 400-mg single dose of two quinolones in a phase I study. The area under the bactericidal curv...
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| Publicado no: | Antimicrob Agents Chemother |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163827/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9145846/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.5.927 |
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