Suspicion of quinolone active metabolite following discrepancy between predicted and experimental urine bactericidal activities.
The prediction of urine antibacterial activity from pharmacological and microbiological parameters was assessed by using experimental urine levels and urine bactericidal titers determined up to 72 h after a 400-mg single dose of two quinolones in a phase I study. The area under the bactericidal curv...
Guardat en:
| Publicat a: | Antimicrob Agents Chemother |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
1997
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163827/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9145846/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.5.927 |
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