Behavior of amphotericin B lipid complex in plasma in vitro and in the circulation of rats.

Amphotericin B lipid complex (ABLC) shows reduced toxicity relative to that of amphotericin B deoxycholate (AmB-d) while maintaining antifungal activity. Rat blood or plasma was spiked with ABLC in vitro. Released amphotericin B was separated from the parent material by centrifugation. At early time...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Bhamra, R, Sa'ad, A, Bolcsak, L E, Janoff, A S, Swenson, C E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163820/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9145839/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.5.886
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