Behavior of amphotericin B lipid complex in plasma in vitro and in the circulation of rats.

Amphotericin B lipid complex (ABLC) shows reduced toxicity relative to that of amphotericin B deoxycholate (AmB-d) while maintaining antifungal activity. Rat blood or plasma was spiked with ABLC in vitro. Released amphotericin B was separated from the parent material by centrifugation. At early time...

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Hauptverfasser: Bhamra, R, Sa'ad, A, Bolcsak, L E, Janoff, A S, Swenson, C E
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1997
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC163820/
https://ncbi.nlm.nih.gov/pubmed/9145839
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