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Flavonoid fisetin promotes ERK-dependent long-term potentiation and enhances memory
Small molecules that activate signaling pathways used by neurotrophic factors could be useful for treating CNS disorders. Here we show that the flavonoid fisetin activates ERK and induces cAMP response element-binding protein (CREB) phosphorylation in rat hippocampal slices, facilitates long-term po...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2006
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1637622/ https://ncbi.nlm.nih.gov/pubmed/17050681 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607822103 |
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