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Identification of New Human Origins of DNA Replication by an Origin-Trapping Assay

Metazoan genomes contain thousands of replication origins, but only a limited number have been characterized so far. We developed a two-step origin-trapping assay in which human chromatin fragments associated with origin recognition complex (ORC) in vivo were first enriched by chromatin immunoprecip...

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Detalhes bibliográficos
Main Authors: Gerhardt, Jeannine, Jafar, Samira, Spindler, Mark-Peter, Ott, Elisabeth, Schepers, Aloys
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636883/
https://ncbi.nlm.nih.gov/pubmed/16954389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01392-06
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