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The Middle Domain of Hsp90 Acts as a Discriminator between Different Types of Client Proteins
The mechanism of client protein activation by Hsp90 is enigmatic, and it is uncertain whether Hsp90 employs a common route for all proteins. Using a mutational analysis approach, we investigated the activation of two types of client proteins, glucocorticoid receptor (GR) and the kinase v-Src by the...
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| Główni autorzy: | , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society for Microbiology
2006
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1636778/ https://ncbi.nlm.nih.gov/pubmed/16982694 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02188-05 |
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