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Signaling within a Coactivator Complex: Methylation of SRC-3/AIB1 Is a Molecular Switch for Complex Disassembly

Recent studies indicate that steroid receptor-mediated transcriptional initiation is a cyclical process involving multiple rounds of coactivator assembly and disassembly. Steroid receptor coactivator 3 (SRC-3) coactivator phosphorylation has been shown to regulate coactivator complex assembly, but t...

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Bibliographic Details
Main Authors: Feng, Qin, Yi, Ping, Wong, Jiemin, O'Malley, Bert W.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636757/
https://ncbi.nlm.nih.gov/pubmed/16923966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00568-06
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