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In Vivo Requirement of the Small Subunit of U2AF for Recognition of a Weak 3′ Splice Site
The U2 snRNP auxiliary factor (U2AF) is an essential splicing factor composed of two subunits, a large, 65-kDa subunit (U2AF(65)) and a small subunit, U2AF(35). U2AF(65) binds to the polypyrimidine tract upstream from the 3′ splice site and promotes U2 snRNP binding to the pre-mRNA. Based on in vitr...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1636752/ https://ncbi.nlm.nih.gov/pubmed/16940179 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00350-06 |
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