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Identification of Genes Controlled by the Pregnane X Receptor by Microarray Analysis of mRNAs from Pregnenolone 16α-carbonitrile Treated Rats
Mammalian liver contains a Pregnane X Receptor (NR1I2), which binds drugs and other xenobiotics, and stimulates (or suppresses) expression of numerous genes involved in the metabolic elimination of foreign compounds and some toxic endogenous substances. In the present study we used microarray analys...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1636678/ https://ncbi.nlm.nih.gov/pubmed/16997903 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfl116 |
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