Phosphorylation of HIV-1 Tat by CDK2 in HIV-1 transcription

BACKGROUND: Transcription of HIV-1 genes is activated by HIV-1 Tat protein, which induces phosphorylation of RNA polymerase II (RNAPII) C-terminal domain (CTD) by CDK9/cyclin T1. Earlier we showed that CDK2/cyclin E phosphorylates HIV-1 Tat in vitro. We also showed that CDK2 induces HIV-1 transcript...

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Auteurs principaux: Ammosova, Tatyana, Berro, Reem, Jerebtsova, Marina, Jackson, Angela, Charles, Sharroya, Klase, Zachary, Southerland, William, Gordeuk, Victor R, Kashanchi, Fatah, Nekhai, Sergei
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2006
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636661/
https://ncbi.nlm.nih.gov/pubmed/17083724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-3-78
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