The BAH domain facilitates the ability of human Orc1 protein to activate replication origins in vivo

Selection of initiation sites for DNA replication in eukaryotes is determined by the interaction between the origin recognition complex (ORC) and genomic DNA. In mammalian cells, this interaction appears to be regulated by Orc1, the only ORC subunit that contains a bromo-adjacent homology (BAH) doma...

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Hlavní autoři: Noguchi, Kohji, Vassilev, Alex, Ghosh, Soma, Yates, John L, DePamphilis, Melvin L
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636626/
https://ncbi.nlm.nih.gov/pubmed/17066079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601396
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