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T-8581, a new orally and parenterally active triazole antifungal agent: in vitro and in vivo evaluations.

T-8581 is a new water-soluble triazole antifungal agent. The geometric mean IC80s (GM-IC80S; where the IC80 is the lowest drug concentration which reduced the optical density at 630 nm by 80% compared with the optical density at 630 nm of the drug-free control) for Candida albicans were as follows:...

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Izdano u:Antimicrob Agents Chemother
Glavni autori: Yotsuji, A, Shimizu, K, Araki, H, Fujimaki, K, Nishida, N, Hori, R, Annen, N, Yamamoto, S, Hayakawa, H, Imaizumi, H, Watanbe, Y, Narita, H
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 1997
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163655/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8980750/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.1.30
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