In Vitro and In Vivo Antifungal Activities of TAK-456, a Novel Oral Triazole with a Broad Antifungal Spectrum

TAK-456 is a novel oral triazole compound with potent and broad-spectrum in vitro antifungal activity and strong in vivo efficacy against Candida albicans and Aspergillus fumigatus. TAK-456 inhibited sterol synthesis of C. albicans and A. fumigatus by 50% at 3 to 11 ng/ml. TAK-456 showed strong in v...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Tsuchimori, Noboru, Hayashi, Ryogo, Kitamoto, Naomi, Asai, Kentaro, Kitazaki, Tomoyuki, Iizawa, Yuji, Itoh, Katsumi, Okonogi, Kenji
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC127141/
https://ncbi.nlm.nih.gov/pubmed/11959573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.5.1388-1393.2002
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados