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Modeling dual pathways for the metazoan spindle assembly checkpoint
Using computational modeling, we investigate mechanisms of signal transduction. We focus on the spindle assembly checkpoint, where a single unattached kinetochore is able to signal to prevent cell cycle progression. The inhibitory signal switches off rapidly once spindle microtubules have attached t...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1636528/ https://ncbi.nlm.nih.gov/pubmed/17065324 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0603174103 |
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