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A single dose of doxorubicin-functionalized bow-tie dendrimer cures mice bearing C-26 colon carcinomas
The antitumor effect of doxorubicin (DOX) conjugated to a biodegradable dendrimer was evaluated in mice bearing C-26 colon carcinomas. An asymmetric biodegradable polyester dendrimer containing 8–10 wt % DOX was prepared. The design of the dendrimer carrier optimized blood circulation time through s...
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Main Authors: | , , , , , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
National Academy of Sciences
2006
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1636509/ https://ncbi.nlm.nih.gov/pubmed/17075050 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607705103 |
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