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β-Catenin stabilizes Cyclooxygenase-2 mRNA by interacting with AU-rich elements of 3′-UTR

Cyclooxygenase-2 (COX-2) mRNA is induced in the majority of human colorectal carcinomas. Transcriptional regulation plays a key role in COX-2 expression in human colon carcinoma cells, but post-transcriptional regulation of its mRNA is also critical for tumorigenesis. Expression of COX-2 mRNA is reg...

詳細記述

保存先:
書誌詳細
主要な著者: Lee, Hee Kyu, Jeong, Sunjoo
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2006
主題:
RNA
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636482/
https://ncbi.nlm.nih.gov/pubmed/17040897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl698
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