AU-RICH ELEMENTS IN THE 3′-UTR REGULATE THE STABILITY OF THE 141 AMINO ACID ISOFORM OF PARATHYROID HORMONE-RELATED PROTEIN mRNA

We demonstrated previously that parathyroid hormone-related protein (PTHrP) 1-141 mRNA is the least stable of three isoforms and is the only isoform that is stabilized by TGF-β. In order to understand how PTHrP mRNA is stabilized by TGF-β, we first sought to elucidate the mechanism(s) that are respo...

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Detalhes bibliográficos
Main Authors: Luchin, Alexander I., Nadella, Murali V.P., Thudi, Nanda K., Dirksen, Wessel P., Gulati, Parul, Fernandez, Soledad A., Rosol, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529141/
https://ncbi.nlm.nih.gov/pubmed/22960231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2012.08.015
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