Non-random, individual-specific methylation profiles are present at the sixth CTCF binding site in the human H19/IGF2 imprinting control region

Expression of imprinted genes is classically associated with differential methylation of specific CpG-rich DNA regions (DMRs). The H19/IGF2 locus is considered a paradigm for epigenetic regulation. In mice, as in humans, the essential H19 DMR—target of the CTCF insulator—is located between the two g...

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Bibliographic Details
Main Authors: Tost, Jörg, Jammes, Hélène, Dupont, Jean-Michel, Buffat, Christophe, Robert, Brigitte, Mignot, Thérèse-Marie, Mondon, Françoise, Carbonne, Bruno, Siméoni, Umberto, Grangé, Gilles, Kerjean, Antoine, Ferré, Françoise, Gut, Ivo Glynne, Vaiman, Daniel
Format: Artigo
Language:Inglês
Published: Oxford University Press 2006
Subjects:
Molecular Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636469/
https://ncbi.nlm.nih.gov/pubmed/17012269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl657
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