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Resistance to amikacin and isepamicin in rabbits with experimental endocarditis of an aac(6')-Ib-bearing strain of Klebsiella pneumoniae susceptible in vitro.

The effect of production of the aminoglycoside 6'-N-acetyltransferase [AAC(6')-IB] in Klebsiella pneumoniae on the outcome of amikacin and isepamicin treatment of rabbits with experimental endocarditis was assessed. Isogenic high-level (Hi) and low-level (Lo) AAC(6')-Ib-producing transconjugants (T)...

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Bibliografiska uppgifter
I publikationen:Antimicrob Agents Chemother
Huvudupphov: Caulin, E, Coutrot, A, Carbon, C, Collatz, E
Materialtyp: Artigo
Språk:Inglês
Utgiven: American Society for Microbiology (ASM) 1996
Ämnen:
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163634/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9124853/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.12.2848
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