High-level fluoroquinolone resistance in Streptococcus pneumoniae requires mutations in parC and gyrA.

The mechanism of high-level fluoroquinolone resistance was studied in strains of Streptococcus pneumoniae, either selected in vitro or isolated from clinical samples. By using DNA from these high-level-resistant strains, low-level-resistant transformants (MIC of pefloxacin, > or = 32 micrograms/ml;...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Janoir, C, Zeller, V, Kitzis, M D, Moreau, N J, Gutmann, L
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163617/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9124836/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.12.2760
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