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High-level fluoroquinolone resistance in Streptococcus pneumoniae requires mutations in parC and gyrA.

The mechanism of high-level fluoroquinolone resistance was studied in strains of Streptococcus pneumoniae, either selected in vitro or isolated from clinical samples. By using DNA from these high-level-resistant strains, low-level-resistant transformants (MIC of pefloxacin, > or = 32 micrograms/m...

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Bibliografische gegevens
Hoofdauteurs: Janoir, C, Zeller, V, Kitzis, M D, Moreau, N J, Gutmann, L
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1996
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC163617/
https://ncbi.nlm.nih.gov/pubmed/9124836
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