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Engineering of Primary Carbohydrate Metabolism for Increased Production of Actinorhodin in Streptomyces coelicolor

The objectives of the current studies were to determine the roles of key enzymes in central carbon metabolism in the context of increased production of antibiotics in Streptomyces coelicolor. Genes for glucose-6-phosphate dehydrogenase and phosphoglucomutase (Pgm) were deleted and those for the acet...

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Detalhes bibliográficos
Main Authors: Ryu, Yong-Gu, Butler, Michael J., Chater, Keith F., Lee, Kye Joon
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636169/
https://ncbi.nlm.nih.gov/pubmed/16950896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01308-06
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