Engineering of Primary Carbon Metabolism for Improved Antibiotic Production in Streptomyces lividans

Deletions were made in Streptomyces lividans in either of two genes (zwf1 and zwf2) encoding isozymes of glucose-6-phosphate dehydrogenase, the first enzyme in the oxidative pentose phosphate pathway (PPP). Each mutation reduced the level of Zwf activity to approximately one-half that observed in th...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Butler, Michael J., Bruheim, Per, Jovetic, Srdjan, Marinelli, Flavia, Postma, Pieter W., Bibb, Mervyn J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2002
Gaiak:
Physiology and Biotechnology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC126421/
https://ncbi.nlm.nih.gov/pubmed/12324314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.68.10.4731-4739.2002
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