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Engineering of Primary Carbon Metabolism for Improved Antibiotic Production in Streptomyces lividans
Deletions were made in Streptomyces lividans in either of two genes (zwf1 and zwf2) encoding isozymes of glucose-6-phosphate dehydrogenase, the first enzyme in the oxidative pentose phosphate pathway (PPP). Each mutation reduced the level of Zwf activity to approximately one-half that observed in th...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2002
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC126421/ https://ncbi.nlm.nih.gov/pubmed/12324314 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.68.10.4731-4739.2002 |
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