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Structure of vaccinia virus thymidine kinase in complex with dTTP: insights for drug design
BACKGROUND: Development of countermeasures to bioterrorist threats such as those posed by the smallpox virus (variola), include vaccination and drug development. Selective activation of nucleoside analogues by virus-encoded thymidine (dThd) kinases (TK) represents one of the most successful strategi...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2006
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1636055/ https://ncbi.nlm.nih.gov/pubmed/17062140 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-6-22 |
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