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Control of dTTP pool size by anaphase promoting complex/cyclosome is essential for the maintenance of genetic stability
Anaphase promoting complex/cyclosome (APC/C)-mediated proteolysis is essential for chromosome segregation, mitotic exit, and G1 entry. Here, we show the importance of APC/C in the control of dTTP pool size in mammalian cells. Two enzymes, thymidine kinase 1 (TK1) and thymidylate kinase (TMPK), invol...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
2005
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1186191/ https://ncbi.nlm.nih.gov/pubmed/16103219 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1322905 |
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