Efficient technique for screening drugs for activity against Trypanosoma cruzi using parasites expressing beta-galactosidase.
A new drug screening method was devised utilizing Trypanosoma cruzi cells that express the Escherichia coli beta-galactosidase gene. Transfected parasites catalyze a colorimetric reaction with chlorophenol red beta-D-galactopyranoside as substrate. Parasite growth in the presence of drugs in microti...
Збережено в:
| Опубліковано в:: | Antimicrob Agents Chemother |
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| Автори: | , , , |
| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
American Society for Microbiology (ASM)
1996
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| Предмети: | |
| Онлайн доступ: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163582/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8913471/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.11.2592 |
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