Emergence of protease inhibitor resistance mutations in human immunodeficiency virus type 1 isolates from patients and rapid screening procedure for their detection.

Patient human immunodeficiency virus type 1 (HIV-1) isolates that are resistant to protease inhibitors may contain amino acid substitutions L10I/V, M46L/I, G-48V, L63P, V82A/F/T, I84V, and L90M in the protease gene. Substitutions at positions 82 and/or 90 occur in variants that display high levels o...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Vasudevachari, M B, Zhang, Y M, Imamichi, H, Imamichi, T, Falloon, J, Salzman, N P
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1996
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163570/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8913459/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.11.2535
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