Harnessing a High Cargo-Capacity Transposon for Genetic Applications in Vertebrates

Viruses and transposons are efficient tools for permanently delivering foreign DNA into vertebrate genomes but exhibit diminished activity when cargo exceeds 8 kilobases (kb). This size restriction limits their molecular genetic and biotechnological utility, such as numerous therapeutically relevant...

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Autors principals: Balciunas, Darius, Wangensteen, Kirk J, Wilber, Andrew, Bell, Jason, Geurts, Aron, Sivasubbu, Sridhar, Wang, Xin, Hackett, Perry B, Largaespada, David A, McIvor, R. Scott, Ekker, Stephen C
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2006
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635535/
https://ncbi.nlm.nih.gov/pubmed/17096595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0020169
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