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Chromosomal translocations involving the MLL gene: molecular mechanisms

A wide array of recurrent, non-random chromosomal translocations are associated with hematologic malignancies; experimental models have clearly demonstrated that many of these translocations are causal events during malignant transformation. Translocations involving the MLL gene are among the most c...

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Bibliographic Details
Main Author: Aplan, Peter D.
Format: Artigo
Language:Inglês
Published: 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635494/
https://ncbi.nlm.nih.gov/pubmed/16797254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2006.05.034
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