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Interaction of human GTP cyclohydrolase I with its splice variants

Tetrahydrobiopterin is an essential cofactor for aromatic amino acid hydroxylases, ether lipid oxidase and nitric oxide synthases. Its biosynthesis in mammals is regulated by the activity of the homodecameric enzyme GCH (GTP cyclohydrolase I; EC 3.5.4.16). In previous work, catalytically inactive hu...

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Detalles Bibliográficos
Autores principales: Pandya, Maya J., Golderer, Georg, Werner, Ernst R., Werner-Felmayer, Gabriele
Formato: Artigo
Lenguaje:Inglês
Publicado: Portland Press Ltd. 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635435/
https://ncbi.nlm.nih.gov/pubmed/16848765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060765
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