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Interaction of human GTP cyclohydrolase I with its splice variants

Tetrahydrobiopterin is an essential cofactor for aromatic amino acid hydroxylases, ether lipid oxidase and nitric oxide synthases. Its biosynthesis in mammals is regulated by the activity of the homodecameric enzyme GCH (GTP cyclohydrolase I; EC 3.5.4.16). In previous work, catalytically inactive hu...

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Detalhes bibliográficos
Main Authors: Pandya, Maya J., Golderer, Georg, Werner, Ernst R., Werner-Felmayer, Gabriele
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635435/
https://ncbi.nlm.nih.gov/pubmed/16848765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060765
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