Potent activity of 2'-beta-fluoro-2',3'-dideoxyadenosine against human immunodeficiency virus type 1 infection in hu-PBL-SCID mice.

A new antiretroviral agent, 2'-beta-fluoro-2',3'-dideoxyadenosine (FddA), is an acid-stable compound whose triphosphate form is a potent reverse transcriptase inhibitor with in vitro anti-human immunodeficiency virus (HIV) activity and a favorable pharmacokinetic profile. Severe combined immunodefic...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Ruxrungtham, K, Boone, E, Ford, H, Driscoll, J S, Davey, R T, Lane, H C
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1996
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163536/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8891146/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.10.2369
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