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Nonadaptive Regulation of ERK2 in Dictyostelium: Implications for Mechanisms of cAMP Relay

It is assumed that ERK2 in Dictyostelium is subject to adaptive regulation in response to constant extracellular ligand stimulation. We now show, to the contrary, that ERK2 remains active under continuous stimulation, differing from most ligand-activated pathways in chemotactically competent Dictyos...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Brzostowski, Joseph A., Kimmel, Alan R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635358/
https://ncbi.nlm.nih.gov/pubmed/16870702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-05-0376
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