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Nonadaptive Regulation of ERK2 in Dictyostelium: Implications for Mechanisms of cAMP Relay

It is assumed that ERK2 in Dictyostelium is subject to adaptive regulation in response to constant extracellular ligand stimulation. We now show, to the contrary, that ERK2 remains active under continuous stimulation, differing from most ligand-activated pathways in chemotactically competent Dictyos...

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Bibliografiska uppgifter
Huvudupphovsmän: Brzostowski, Joseph A., Kimmel, Alan R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society for Cell Biology 2006
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635358/
https://ncbi.nlm.nih.gov/pubmed/16870702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-05-0376
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