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A real-time assay for monitoring nucleic acid cleavage by quadruplex formation

Direct and straightforward methods to follow nucleic acid cleavage are needed. A spectrophotometric quadruplex formation assay (QFA) was developed, which allows real-time monitoring of site-specific cleavage of nucleic acids. QFA was applied to study both protein and nucleic acid restriction enzymes...

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Detalhes bibliográficos
Autor principal: Kankia, Besik I.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635264/
https://ncbi.nlm.nih.gov/pubmed/17071965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl594
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