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Calcineurin Promotes Infection of the Cornea by Candida albicans and Can Be Targeted To Enhance Fluconazole Therapy

In an established Candida albicans murine keratitis model, combination therapy with ophthalmic preparations of fluconazole and cyclosporine A (CsA) demonstrated in vivo drug synergy and effectively resolved wild-type C. albicans infection more rapidly than monotherapy with either drug. Calcineurin,...

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Hlavní autoři: Onyewu, Chiatogu, Afshari, Natalie A., Heitman, Joseph
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635197/
https://ncbi.nlm.nih.gov/pubmed/16923949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00393-06
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