Novel Streptomycin Resistance Gene from Mycobacterium fortuitum

We have isolated the aph(3")-Ic gene, encoding an aminoglycoside 3"-O-phosphotransferase [APH(3")-Ic], from a genomic library of an environmental Mycobacterium fortuitum strain, selecting for streptomycin resistance. APH(3")-Ic phosphorylates and inactivates streptomycin. Similar...

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Bibliographic Details
Main Authors: Ramón-García, Santiago, Otal, Isabel, Martín, Carlos, Gómez-Lus, Rafael, Aínsa, José A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635185/
https://ncbi.nlm.nih.gov/pubmed/16954315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00223-06
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