Vitamin D receptor in chondrocytes promotes osteoclastogenesis and regulates FGF23 production in osteoblasts

Genomic actions induced by 1α25-dihydroxyvitamin D(3) [1,25(OH)(2)D(3)] are crucial for normal bone metabolism, mainly because they regulate active intestinal calcium transport. To evaluate whether the vitamin D receptor (VDR) has a specific role in growth-plate development and endochondral bone for...

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Hlavní autoři: Masuyama, Ritsuko, Stockmans, Ingrid, Torrekens, Sophie, Van Looveren, Riet, Maes, Christa, Carmeliet, Peter, Bouillon, Roger, Carmeliet, Geert
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2006
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635166/
https://ncbi.nlm.nih.gov/pubmed/17099775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI29463
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