Vitamin D sterols increase FGF23 expression by stimulating osteoblast and osteocyte maturation in CKD bone

Impaired osteoblast and osteocyte maturation contribute to mineralization defects and excess FGF23 expression in CKD bone. Vitamin D sterols decrease osteoid accumulation and increase FGF23 expression; these agents also increase osteoblast maturation in vitro but a link between changes in bone cell...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Bone
Prif Awduron: Pereira, Renata C., Salusky, Isidro B., Bowen, Richard E., Freymiller, Earl G., Wesseling-Perry, Katherine
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6715148/
https://ncbi.nlm.nih.gov/pubmed/31377240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2019.07.026
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