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erbB2 is required for G protein-coupled receptor signaling in the heart
erbB2/Her2, a ligandless receptor kinase, has pleiotropic effects on mammalian development and human disease. The absence of erbB2 signaling in cardiac myocytes results in dilated cardiomyopathy in mice, resembling the cardiotoxic effects observed in a subset of breast cancer patients treated with t...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1635098/ https://ncbi.nlm.nih.gov/pubmed/17043217 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607499103 |
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