Evidence that high-dosage zidovudine at time of retrovirus exposure reduces antiviral efficacy.

The antiviral efficacy of prophylactic 3'-azido-3'-deoxythymidine (AZT) therapy administered by continuous infusion or intermittent injection was compared in pediatric cats infected with feline leukemia virus. A 4-week treatment regimen of AZT was initiated at -48, 8, or 96 h postinfection (p.i.). F...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Mathes, L E, Hayes, K A, Kociba, G
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163495/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8878603/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.9.2183
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